• Register
  • Login
  • Bookmark this page!
Skip Navigation LinksHome Page    >    Tests during the pregnancy    >    Polyhydramnios (Excess Amniotic Fluid)
Pregnancy links...
Health links...
Genetics links...
Medical links...
Autism links...
Other links...

Polyhydramnios (Excess Amniotic Fluid)

What is this and what is its significance?

Polyhydramnios is a subjective finding evaluated by the examining ultrasonographer. It occurs in 1% - 3% of pregnancies and is especially common in twin pregnancies. In most cases, it appears at the end of the second trimester or during the third trimester of pregnancy.

The common causes of polyhydramnios are as follows:

  • Maternal diabetes

  • A monozygotic twin pregnancy, as mentioned above. The appearance of polyhydramnios in the early weeks of gestation (18 - 24) of a twin pregnancy indicates either that the twins are identical (monozygotic), or that a pathological condition exists where blood is transferred from one fetus to the other (twin to twin transfusion). In this condition blood vessels develop that connect the two fetuses to each other, and this results in a situation where one fetus has a shortage of blood (anemia), and the other (the recipient) has a surplus (polycythemia). This condition can sometimes lead to several additional problems such as differences in growth and even heart failure in one of the fetuses.

  • Fetal defects - the frequency of associated defects in a fetus in the presence of polyhydramnios varies according to different reports. In cases of severe polyhydramnios, the risk for additional defects may reach a considerable level. The reported defects are: open central nervous system defects (neural tube defects), placental tumors, intestinal obstructions (especially of the esophagus), defects causing pressure on the fetal lungs (skeletal disorders, pulmonary cysts, etc.), defects in the fetus's limbs causing reduced motility, and diseases associated with muscular problems such as myotonic dystrophy, etc.

  • Chromosome disorders - there are various reports on the relationship between polyhydramnios and chromosome disorders. When additional defects are diagnosed, the risk that there is an associated chromosome disorder increases significantly, but even in cases where marked polyhydramnios occurs as an isolated finding, where no obvious cause has been found (such as diabetes or twins), there is approximately a 5% risk of an associated chromosome disorder. Recent studies have shown a lesser rate of chromosomal anomalies in cases of polyhydramnios if no other abnormalities are found in the fetus.

What should be done if polyhydramnios is diagnosed?

  • The mother should be investigated for diabetes by performing a glucose tolerance test.

  • Ultrasound examination should be performed to look for fetal defects and repeated in order to monitor the quantity of amniotic fluid. In cases where the quantity increases and there is a risk that the mother may go into early labor or develop breathing difficulties, the physician may consider more active intervention. The same applies in cases of identical (monozygotic) twin pregnancies.

  • The parents should be referred for genetic counseling in order to receive a full explanation of the condition, its significance and implications, whether further investigations should be performed, and to discuss the question of amniocentesis. The "gold-standard" threshold for recommendation of amniocentesis is a risk of Down syndrome greater than 1:386 based on the results of the biochemical marker screening tests, and when the weighted risk is equal to or higher than this amniocentesis is generally recommended. However, the presence of polyhydramnion in the fetus may statistically increase the risk of Down syndrome. Therefore in these cases some physicians suggest that this should be integrated with the results of the biochemical screening tests and the new threshold for recommending amniocentesis is a risk for Down syndrome of greater than 1:1000 in the biochemical marker screening tests.

  • It is especially important to offer genetic counseling when there is no obvious reason for the polyhydramnios, or when the polyhydramnios is very marked or other defects are also present.

Haven't found what you're looking for? Search for it here:   
Comments (15)

Tuesday, June 27, 2017 4:23 AM
(1) smith  says:

Quickbook support phone number

Quickbooks Support Number @ http://www.quickbookssupportphone-number.com/

Tuesday, June 27, 2017 5:00 AM
(2) smith  says:

Quickbook support phone number

Quicken Support Number @ http://www.quicken.support-phonenumber.com/

Tuesday, June 27, 2017 5:00 AM
(3) smith  says:

Quickbook support phone number

Sage Support Number @ http://www.sage.support-phonenumber.com/

Wednesday, June 28, 2017 11:08 PM
(4) Anjilo smith  says:

Packers and Movers New York

http://www.waydm.com/us/packers-and-movers/new-york/ http://www.waydm.com/us/packers-and-movers/san-francisco/ http://www.waydm.com/us/packers-and-movers/los-angeles/

Thursday, September 14, 2017 11:51 PM
(5) Alikes smith  says:

QuickBooks Help


Friday, September 15, 2017 12:08 AM
(6) Alikes smith  says:

QuickBooks Help


Friday, September 15, 2017 12:25 AM
(7) Alikes smith  says:

Quicken Help


Friday, September 15, 2017 12:39 AM
(8) Alikes smith  says:

Quicken Help


Friday, September 15, 2017 12:50 AM
(9) Alikes smith  says:

Sage Help


Friday, September 15, 2017 1:02 AM
(10) Alikes smith  says:

Sage Help


Monday, December 11, 2017 1:07 PM
(11) ??? ??? ??????  says:

??? ??? ??????

http://uraltpp.com/%D8%B4%D8%B1%D9%83%D8%A9-%D9%86%D9%82%D9%84-%D8%B9%D9%81%D8%B4-%D8%A8%D8%AE%D9%85%D9%8A%D8%B3-%D9%85%D8%B4%D9%8A%D8%B7-%D8%A7%D8%A8%D9%87%D8%A7/ ???? ??? ??? ????? ???? http://uraltpp.com/ ???? ??? ??? ?????? http://uraltpp.com/%D8%B4%D8%B1%D9%83%D8%A9-%D9%86%D9%82%D9%84-%D8%B9%D9%81%D8%B4-%D8%A8%D9%86%D8%AC%D8%B1%D8%A7%D9%86-%D8%B4%D8%B1%D9%88%D8%B1%D9%87/ ???? ??? ??? ??????

Monday, December 11, 2017 1:16 PM
(12) east-eldmam  says:

Furniture transfer company in Dammam

Thanks for post this helpful post - Please visit for More information about - http://goo.gl/iAJsRz http://www.east-eldmam.com http://goo.gl/qga5YC http://goo.gl/Vv4Sp9 http://goo.gl/52zZFy http://goo.gl/VgTwlW http://goo.gl/SHZHnV http://goo.gl/1kXTpJ http://goo.gl/DuLCNP http://goo.gl/iksDnr http://goo.gl/Etnu4A http://goo.gl/x3BKPU http://goo.gl/hAu2Pm http://goo.gl/7VW8I5 http://goo.gl/3NkrF1

Monday, December 11, 2017 1:23 PM
(13) jumperads  says:

Furniture transfer company Mecca

http://jumperads.com/ http://jumperads.com/transfer-furniture-riyadh.html http://jumperads.com/transfer-furniture-jeddah.html http://jumperads.com/transfer-furniture-dammam.html http://jumperads.com/transfer-furniture-medina-almonawara.html http://jumperads.com/transfer-furniture-taif.html http://jumperads.com/transfer-furniture-mecca.html http://jumperads.com/transfer-furniture-yanbu.html

Monday, December 11, 2017 2:11 PM
(14) emc-mee  says:

Furniture transfer company Riydah

http://emc-mee.com/blog.html http://emc-mee.com/tanks-cleaning-company-jeddah.html http://emc-mee.com/water-leaks-detection-isolate-company-dammam.html http://emc-mee.com/anti-insects-company-dammam.html http://emc-mee.com/tanks-cleaning-company-jeddah.html http://emc-mee.com/ http://emc-mee.com/movers-in-riyadh-company.html http://emc-mee.com/transfer-furniture-jeddah.html

Monday, December 11, 2017 2:12 PM
(15) domyate  says:

Furniture transfer company Madinha

http://www.domyate.com/2015/08/30/furniture-transport-company-in-almadinah http://www.domyate.com/2016/06/05/transfer-furniture-medina-almonawara http://www.domyate.com/2016/06/05/transfer-furniture-mecca http://www.domyate.com/2016/06/05/transfer-furniture-riyadh http://www.domyate.com/2016/06/05/transfer-furniture-jeddah http://www.domyate.com/2017/08/10/movers-company-mecca-naql/ http://www.domyate.com http://treeads.net/

Leave a Comment
Email (will not be published)
Website (optional)
Your Comment

Line and paragraph breaks are automatic.

Please type the characters you see in the picture:

All content Copyright © 2009-2011, Genetics of Pregnancy Encyclopedia Corporation. All rights reserved.